Antilipemic Agents
Lilley Pharmacology Text: Chapter 27
Original Text modified by:
Anita A. Kovalsky, R.N., M.N.Ed.
Professor of Nursing
Original PPT by:
Professor Pat Woodbery, ARNP
Professor of Nursing
Understanding Antilepemic Drugs
You must understand
Cholesterol
Triglycerides
Lipoproteins
Lipid Forms
Cholesterol Balance
Liver and Cholesterol
Lilley pg. 434
Cholesterol and Coronary Heart
Disease
Lilley pg. 434
Treatment Decisions
Lilley pp. 436-437
Use of Antilipemics
Lilley pg. 436
How do Antilipemic Drugs Work?
Alter production, Alter metabolism, Assist in removal of lipids and lipoproteins
Who takes Antilipemic Drugs?
Clients with elevated cholesterol:
When 6 months of life style changes and diet changes do not lower cholesterol
Those with coronary artery disease (CAD)
Those with family history
Those with other disease processes: DM, HTN, SMOKERS)
Prototype Drug:
Simvastatin (Zocor)
(Trade name in parentheses)
Lilley pg. 439
STATIN DRUG
Inhibits an enzyme (hydroxymethylglutaryl-coenzyme A reductase) required for hepatic synthesis of cholesterol
Nursing Actions
Check for lowering of cholesterol
Take in the evening
Observe for side effects
GI problems
Abnormal liver enzymes
Muscle pains
Client Teaching
The END