Notes

Slide Show

Outline

2 Drugs that Affect Blood Coagulation

3 Who Needs Anticoagulants, Antiplatelets, Thrombolytics?

4 What Upsets the Balance

between

Thrombogenesis and Thrombolysis?Atherosclerosis

Accidents

Medical Interventions

Drugs

5

How do Thrombotic Events look?Thrombophlebitis

Deep vein thrombosis (DVT)

Pulmonary Embolus (PE)

Myocardial Infarction (MI)

6 Prototype AnticoagulantsHeparin

Enoxaparin

(Lovenox)

Warfarin(Coumadin)

7

Anticoagulants

What you need to know!Heparin:   Page 415

Enoxaparin (Lovenox):  Page 415

Warfarin (Coumadin):  Page 415

8 Prototype

Antiplatelet AgentsAcetylsalicylic Acid (Aspirin)

Clopidogrel (Plavix)

9

Antiplatelet Agents

What you need to know!

Goals

Take Correctly

Monitor for positive and negative effects

Prevent trauma

Interventions

Exercise

Avoid trauma

10 Systemic Hemostatic Agents

11 Patient TeachingIncrease risk of BLEEDING

Potential for clot formation

Periodic blood tests

? OTC

12 Regulation of MedicatonsaPTT (1.5 -2 x control) = Heparin

INR (2-3 x) = Warfarin

PT (1.5-2.5 x control) = Warfarin

13 Nursing ACTIONSRationale for drug

Correct Dose

Site Assessment

Check Labs for therapeutic effects

Adverse Effects