1
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2
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- Mother Rh– & Father Rh+
- Rh+ Fetus’ blood gets into maternal circulation
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3
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- Antibodies are made against Rh+
- During second pregnancy with Rh+ fetus, antibodies attack
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4
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- Serious reaction
- RBC agglutination
- Hemolysis
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5
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- Indirect: done on mom to measure the number of Rh+ ANTIBODIES
- Direct: done with infant to detect antibody coated Rh+ RBC’s
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6
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- Indirect Coombs Negative
- Direct Coombs Negative
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7
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- Indirect Coombs positive
- Direct Coombs positive
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8
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- Obtain Blood Type and Rh factor at initial visit
- Hx of Blood Transfusions
- Received RhoGAM?
- Partner Blood Type
- If sensitized assess knowledge of disease
- After birth assess infants Rh factor
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9
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- Early delivery
- Intrauterine transfusion
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10
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- 28 week antibody screen
- If negative, give RhoGAM
- Give again within 72 hours of delivery
- Post AB
- Ectopic
- Amniocentesis
- Stillbirth
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11
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- O mom
- Type A or B fetus
- First infant may be involved
- No tx antepartum
- Hemolysis results in hyperbirubinemia
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