Histamine Causes:
Stimulation of H1
Receptors
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Contraction of smooth muscle= Wheeze
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Stimulation of Vagus = Cough
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Permeability veins = Edema
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Vasodilation = Flushing
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secretions = Mucous
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Stimulation of nerve endings = Pruritus
Stimulation of Vagus causes bronchoconstriciton which is seen by the patient coughing