Histamine Causes:
Stimulation of H1 Receptors
•
Contraction of smooth muscle= Wheeze
•
Stimulation of Vagus = Cough
•
Permeability veins = Edema
•
Vasodilation = Flushing
•
secretions = Mucous
•
Stimulation of nerve endings = Pruritus
Stimulation of Vagus causes bronchoconstriciton which is seen by the patient coughing