Intermediate Acting Insulin
•
Crystals in suspension
(need re-suspending)
•
Cloudy
•
NPH or Isophane (NPH = Neutral Protamine
Hagedorn)
•
Onset
1
1
/
2
hours
•
Peak
4 - 12 hours
•
Duration
up to 24 hours
Isophane or NPH is the most commonly used intermediate insulin.
NPH stands for Neutral Protamine Hagedorn, and protamine is the retarding agent that alters the speed of absorption and action of the insulin.