Copyright © 2002, 1998, Elsevier Science (USA). All rights reserved.
Aminoglycosides
•
Cause serious toxicities:
–
Nephrotoxicity (renal
failure)
–
Ototoxicity (auditory
impairment and
vestibular [eighth cranial
nerve])
•
Must monitor drug
levels, pg 581
Peak 30-60 minutes after dosing
Trough immediately before the next dose!!!